Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock and Cardiac Arrest

Circ Heart Fail. 2018 Sep;11(9):e004905. doi: 10.1161/CIRCHEARTFAILURE.118.004905.

Abstract

Venoarterial extracorporeal membrane oxygenation (VA-ECMO)-also referred to as extracorporeal life support-is a form of temporary mechanical circulatory support and simultaneous extracorporeal gas exchange. The initiation of VA-ECMO has emerged as a salvage intervention in patients with cardiogenic shock, even cardiac arrest refractory to standard therapies. Analogous to veno-venous ECMO for acute respiratory failure, VA-ECMO provides circulatory support and allows time for other treatments to promote recovery or may be a bridge to a more durable mechanical solution in the setting of acute or acute on chronic cardiopulmonary failure. In this review, we provide a brief overview of VA-ECMO, the attendant physiological considerations of peripheral VA-ECMO, and its complications, namely that of left ventricular distention, bleeding, heightened systemic inflammatory response syndrome, thrombosis and thromboembolism, and extremity ischemia or necrosis.

Keywords: extracorporeal membrane oxygenation; heart arrest; hemorrhage; shock, cardiogenic; thrombosis.

Publication types

  • Review

MeSH terms

  • Cardiovascular System / physiopathology*
  • Clinical Decision-Making
  • Extracorporeal Membrane Oxygenation* / adverse effects
  • Extracorporeal Membrane Oxygenation* / mortality
  • Heart Arrest / diagnosis
  • Heart Arrest / mortality
  • Heart Arrest / physiopathology
  • Heart Arrest / therapy*
  • Hemodynamics
  • Humans
  • Lung / physiopathology*
  • Patient Selection
  • Recovery of Function
  • Respiration
  • Risk Assessment
  • Risk Factors
  • Shock, Cardiogenic / diagnosis
  • Shock, Cardiogenic / mortality
  • Shock, Cardiogenic / physiopathology
  • Shock, Cardiogenic / therapy*
  • Treatment Outcome