The Dilemma of Inadvertent Pontine Demyelinosis: A Review of Literature

Cureus. 2018 Aug 21;10(8):e3174. doi: 10.7759/cureus.3174.

Abstract

Osmotic demyelination syndrome is classically associated with a swift adjustment of previously low serum sodium levels which lead to cellular dehydration and subsequent neurological insult. We also review the epidemiology, different postulations to explain the underlying pathophysiology, current diagnostic modalities, subsequent therapeutic interventions used to manage this phenomenon, and the resultant prognosis of this ailment.

Keywords: osmotic demyelination syndrome; sodium correction.

Publication types

  • Review