Does routine use of indocyanine green fluorescence angiography prevent anastomotic leaks? A retrospective cohort analysis

Am J Surg. 2019 Jul;218(1):136-139. doi: 10.1016/j.amjsurg.2018.10.027. Epub 2018 Oct 16.

Abstract

Background: Insufficient perfusion to anastomoses in colorectal surgery is known to lead to complications. This study aims to evaluate whether routine use of fluorescence angiography (FA) alters the incidence of anastomotic leaks after colorectal surgery.

Methods: This was a retrospective study of 554 colorectal resections with and without the use of intraoperative fluorescence angiography. Anastomotic leak rates and whether angiography altered surgical management were the main outcomes measured.

Results: The anastomotic leak rate was found to be 1.3% both with and without use of FA (p > 0.05). Significantly more alterations were made to planned anastomotic site in FA group (n = 13, 5.6%) as compared to the group prior to use of FA in whom no alterations were made (p < 0.05).

Conclusions: No significant difference was found in anastomotic leak rates between the two groups studied. Routine use of fluorescence angiography significantly altered intra-operative decision-making without discernible change in clinical outcome.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anastomotic Leak / diagnosis*
  • Anastomotic Leak / prevention & control*
  • Colorectal Surgery*
  • Coloring Agents*
  • Decision Making
  • Female
  • Fluorescein Angiography*
  • Humans
  • Indocyanine Green*
  • Male
  • Middle Aged
  • Retrospective Studies

Substances

  • Coloring Agents
  • Indocyanine Green