Urine changing from clear to milky-white

Neth J Med. 2018 Oct;76(8):379-380.


After sedation with propofol a young man developed milky-white urine. Urinalysis showed a high concentration of uric acid crystals as being responsible. This phenomenon appears to be dose-dependent and is explained in this report. Since it is harmless and self-limiting no extensive analysis is needed when observed.

Publication types

  • Case Reports

MeSH terms

  • Anesthetics, Intravenous / adverse effects*
  • Crystallization
  • Humans
  • Male
  • Propofol / adverse effects*
  • Uric Acid / urine*
  • Urination Disorders / chemically induced*
  • Urine / chemistry*
  • Young Adult


  • Anesthetics, Intravenous
  • Uric Acid
  • Propofol