Determination of macro, micro, trace essential, and toxic elements in Garcinia cambogia fruit and its anti-obesity commercial products

J Sci Food Agric. 2019 Mar 30;99(5):2455-2462. doi: 10.1002/jsfa.9454. Epub 2018 Dec 13.


Background: Garcinia (Clusiaceae) species are traditionally used as flavoring agents in curries and to cure several human health complications. This study investigated 31 macro, micro, and trace elements in microwave-assisted digested samples of Garcinia cambogia fruit and its anti-obesity commercial products by inductively coupled plasma-optical emission spectroscopy (ICP-OES) and inductively coupled plasma-mass spectrometric (ICP-MS) techniques. The methods were also validated using the coefficient of determination (R2 ), limits of detection and quantification (LOD, LOQ), precision (CV%), analysis of certified reference materials, spiking recovery experiments, and participation in an accredited laboratory proficiency test organized by Food Analysis Performance Assessment Scheme (FAPAS).

Results: Quality assurance confirmed that the methods were efficient and in accordance with criteria set by the Association of Official Analytical Chemists (AOAC). In the elemental analysis, the analyzed macro, micro, and trace essential elements were present in appreciable concentrations, which could meet the human nutritional requirements. Traces of toxic elements were within safe limits.

Conclusion: From the results of the current study, the fruit and its commercial products could be considered potential sources of mineral elements without posing any threats to consumers. © 2018 Society of Chemical Industry.

Keywords: Garcinia cambogia; commercial products; macro elements; toxic elements; trace elements.

MeSH terms

  • Anti-Obesity Agents / chemistry*
  • Anti-Obesity Agents / economics
  • Anti-Obesity Agents / toxicity
  • Fruit / chemistry
  • Garcinia cambogia / chemistry*
  • Garcinia cambogia / toxicity
  • Limit of Detection
  • Mass Spectrometry
  • Plant Extracts / chemistry*
  • Plant Extracts / economics
  • Plant Extracts / toxicity
  • Trace Elements / chemistry*
  • Trace Elements / economics


  • Anti-Obesity Agents
  • Plant Extracts
  • Trace Elements

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