iDog: An Integrated Resource for Domestic Dogs and Wild Canids

Nucleic Acids Res. 2019 Jan 8;47(D1):D793-D800. doi: 10.1093/nar/gky1041.

Abstract

The domestic dog (Canis lupus familiaris) is indisputably one of man's best friends. It is also a fundamental model for many heritable human diseases. Here, we present iDog (http://bigd.big.ac.cn/idog), the first integrated resource dedicated to domestic dogs and wild canids. It incorporates a variety of omics data, including genome sequences assemblies for dhole and wolf, genomic variations extracted from hundreds of dog/wolf whole genomes, phenotype/disease traits curated from dog research communities and public resources, gene expression profiles derived from published RNA-Seq data, gene ontology for functional annotation, homolog gene information for multiple organisms and disease-related literature. Additionally, iDog integrates sequence alignment tools for data analyses and a genome browser for data visualization. iDog will not only benefit the global dog research community, but also provide access to a user-friendly consolidation of dog information to a large number of dog enthusiasts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Databases, Genetic*
  • Dogs
  • Genome / genetics*
  • Genomics
  • Humans
  • Molecular Sequence Annotation
  • Phylogeny
  • RNA-Seq / trends
  • Software*
  • Wolves / genetics