Linking brain tumors and epileptic seizures

Nat Med. 2018 Nov;24(11):1638-1639. doi: 10.1038/s41591-018-0249-6.

Abstract

Mutationally activated BRAFV600E influences the behavior of different types of cells in the brain and leads to promotion of seizures as well as brain tumors, indicating how both can be pharmacologically targeted in the clinic.

Publication types

  • Comment

MeSH terms

  • Brain Neoplasms*
  • Child
  • Epilepsy*
  • Humans
  • Mutation
  • Proto-Oncogene Proteins B-raf
  • Seizures

Substances

  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf