Spontaneous Coronary Artery Dissection: an Overview

Curr Atheroscler Rep. 2018 Oct 29;20(12):58. doi: 10.1007/s11883-018-0761-7.

Abstract

Spontaneous coronary artery dissection (SCAD) is a non-inflammatory, non-atherosclerotic cause of acute myocardial infarction (AMI) that, by definition, is not iatrogenic or due to trauma. It is a condition that predominantly affects pre- or perimenopausal women without the traditional risk factors for cardiovascular disease. PURPOSE OF REVIEW: In this review, we will discuss the epidemiology, diagnosis, and management of this condition, with an emphasis on the ongoing research needed to better understand how to care for patients with SCAD. RECENT FINDINGS: There is a paucity of data related to this condition. However, an American Heart Association consensus statement has recently been released that provides helpful insight. There has also been better characterization of pregnancy-associated SCAD. We have learned much about SCAD over the last decade and greatly increased the identification of this condition by first responders and physicians through research and patient advocacy. However, there is much we still do not know about this condition, and further research, using larger numbers of patients, is greatly needed to better understand this condition.

Keywords: Acute coronary syndrome; Spontaneous coronary artery dissection; women’s heart health.

Publication types

  • Review

MeSH terms

  • Acute Coronary Syndrome* / epidemiology
  • Acute Coronary Syndrome* / etiology
  • Coronary Vessel Anomalies* / complications
  • Coronary Vessel Anomalies* / diagnosis
  • Coronary Vessel Anomalies* / epidemiology
  • Coronary Vessel Anomalies* / therapy
  • Disease Management
  • Female
  • Humans
  • Risk Factors
  • Vascular Diseases / complications
  • Vascular Diseases / congenital*
  • Vascular Diseases / diagnosis
  • Vascular Diseases / epidemiology
  • Vascular Diseases / therapy
  • Women's Health

Supplementary concepts

  • Coronary Artery Dissection, Spontaneous