Sultamicillin in the treatment of superficial skin and soft tissue infections in children

Antimicrob Agents Chemother. 1987 Apr;31(4):663-4. doi: 10.1128/AAC.31.4.663.

Abstract

Fifty-two children with superficial skin and soft tissue infections were randomized to receive sultamicillin or cloxacillin for 7 days. Twenty-one children in each group finished the study. A total of 16 of 21 in the sultamicillin group and 13 of 21 in the cloxacillin group were cured. One child in the sultamicillin group and two in the cloxacillin group failed therapy. Four children who received sultamicillin and six who received cloxacillin had recurrences of lesions. Differences were not statistically significant.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abscess / drug therapy
  • Ampicillin / adverse effects
  • Ampicillin / therapeutic use*
  • Child
  • Child, Preschool
  • Cloxacillin / adverse effects
  • Cloxacillin / therapeutic use
  • Diarrhea / chemically induced
  • Drug Combinations / adverse effects
  • Drug Combinations / therapeutic use
  • Drug Evaluation
  • Female
  • Folliculitis / drug therapy
  • Humans
  • Infant
  • Male
  • Penicillanic Acid / adverse effects
  • Penicillanic Acid / therapeutic use*
  • Random Allocation
  • Skin Diseases, Infectious / drug therapy*
  • Staphylococcal Infections / drug therapy*
  • Staphylococcal Skin Infections / drug therapy*
  • Streptococcal Infections / drug therapy*
  • Sulbactam

Substances

  • Drug Combinations
  • sultamicillin
  • Ampicillin
  • Penicillanic Acid
  • Cloxacillin
  • Sulbactam