Primary lung cancer in patients with previous malignancies: a nationwide study

Thorax. 2019 May;74(5):492-495. doi: 10.1136/thoraxjnl-2018-211891. Epub 2018 Nov 1.


Overall survival of patients with cancer continues to increase and so they receive more frequent CT imaging, making oncological patients a growing population that effectively receives lung cancer screening in the course of daily practice. However, it is currently uncertain how early lung cancer detection in this subgroup of patients should be optimally managed. We describe the relationship between primary lung cancer and prior malignancies in a nationwide cohort, in an attempt to identify possible areas of improvement in nodule management. We found that a substantial number of subjects with lung cancer suffered from a prior malignancy; however, with the exception of otorhinolaryngeal malignancies, they did not show a high absolute risk for lung cancer. Future research should provide more data on how to handle this subgroup of patients in clinical and screening setting.

Keywords: Imaging/CT MRI etc; lung cancer.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Early Detection of Cancer / methods*
  • Female
  • Humans
  • Incidence
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / epidemiology
  • Male
  • Middle Aged
  • Netherlands / epidemiology
  • Population Surveillance*
  • Retrospective Studies
  • Survival Rate / trends
  • Tomography, X-Ray Computed