Giant Cell Arteritis: 2018 Review

Mo Med. Sep-Oct 2018;115(5):468-470.

Abstract

Giant cell arteritis is the most common large vessel vasculitis. Classic symptoms include headaches, scalp tenderness, visual loss and muscle stiffness and pain. First line treatment is with high dose steroids but methotrexate may be of some help in decreasing steroid use. Tocilizumab has been shown to significantly decrease relapse rate and lower steroid cumulative dose.

Publication types

  • Review

MeSH terms

  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Drug Therapy, Combination
  • Giant Cell Arteritis / complications
  • Giant Cell Arteritis / drug therapy*
  • Giant Cell Arteritis / pathology*
  • Headache / etiology
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Methotrexate / therapeutic use*
  • Muscle Rigidity / etiology
  • Scalp / pathology
  • Vision Disorders / etiology

Substances

  • Antibodies, Monoclonal, Humanized
  • Immunosuppressive Agents
  • tocilizumab
  • Methotrexate