Effect of milk-honey mixture on the sleep quality of coronary patients: A clinical trial study

Clin Nutr ESPEN. 2018 Dec;28:132-135. doi: 10.1016/j.clnesp.2018.08.015. Epub 2018 Sep 10.


Background: Admission of patients in coronary care units can lead to sleep disorders due to advanced monitoring and interventions. Inappropriate sleep quality in cardiac patients may be influenced by their health status. So, this study was performed to detect the effect of Milk-honey mixture on sleep status of acute coronary syndrome patients in the coronary care unit.

Methods: A clinical trial study (registered under IRCT.ir with identifier no. IRCT201309285134N7) was conducted with 68 hospitalized patients with the acute coronary syndrome in the coronary care unit of a referral hospital in Semnan, Iran. After hospitalization of patients and selected eligible patients, sleep status of them was measured by Richards-Campbell Sleep Questionnaire in range of 0 to 100 score. Then patients were divided into the intervention and control groups randomly. Patients in the intervention group were received milk-honey mixture twice a day for three days. The control group patients were received routine care. In the third day, sleep quality of patients in the two groups was measured again. Finally, the data were analyzed by descriptive and inferential statistics.

Results: The mean and standard deviation of patients' age was 63.12 ± 32.63. There was no significant difference in sleep scores on the first day of admission between the two groups (P = 0.914). But, on the third day of admission, there was a significant difference in sleep scores between the intervention and the control groups (P = 0.001).

Conclusion: The mixture of milk and honey improves the sleep status of patients. So, it can be considered as an effective and affordable intervention to enhance the sleep quality of patients with the acute coronary syndrome in coronary care units.

Keywords: Coronary care unit; Honey; Milk; Sleep.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Coronary Syndrome / complications*
  • Adult
  • Animals
  • Female
  • Honey*
  • Humans
  • Male
  • Middle Aged
  • Milk*
  • Sleep Wake Disorders / complications
  • Sleep Wake Disorders / diet therapy*
  • Surveys and Questionnaires
  • Treatment Outcome

Associated data

  • IRCT/IRCT201309285134N7