[Post-transplant neurological complications: Guidelines from the francophone Society of bone marrow transplantation and cellular therapy (SFGM-TC)]

Bull Cancer. 2019 Jan;106(1S):S18-S22. doi: 10.1016/j.bulcan.2018.08.015. Epub 2018 Nov 2.
[Article in French]

Abstract

Neurological complications post-allogeneic hematopoietic stem cell transplantation are well-characterized; however, given their variable impact, they remain a significant cause of morbidity. The etiologies for these complications are vast. Causes may be linked to toxicity and infection or could be vascular or tumor-related. Regardless, these complications require early investigation, which is often multidisciplinary and hierarchical. Preventive measures may be considered in some situations. It is essential to respond early and quickly with a diagnosis and the appropriate therapeutic approach when faced with neurological complications. Focusing on the axes of etiology, diagnosis and treatment, this article offers a review of neurological complications post-allogeneic hematopoietic stem cell transplantation.

Keywords: Allograft; Allogreffe; Complications neurologiques; Neurological complications; SFGM-TC.

Publication types

  • Consensus Development Conference
  • Practice Guideline

MeSH terms

  • Bone Marrow Transplantation
  • Cell- and Tissue-Based Therapy
  • Central Nervous System Diseases / diagnosis
  • Central Nervous System Diseases / etiology
  • Central Nervous System Diseases / therapy
  • France
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Nervous System Diseases* / diagnosis
  • Nervous System Diseases* / etiology
  • Nervous System Diseases* / therapy
  • Postoperative Complications* / diagnosis
  • Postoperative Complications* / etiology
  • Postoperative Complications* / therapy
  • Societies, Medical
  • Time Factors
  • Transplantation, Homologous