Recurrent Fusion Gene ADCK4-NUMBL in Cutaneous Squamous Cell Carcinoma Mediates Cell Proliferation

J Invest Dermatol. 2019 Apr;139(4):954-957. doi: 10.1016/j.jid.2018.09.030. Epub 2018 Nov 2.

Authors

Affiliations

¹ Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.
² Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan. Electronic address: mjin@kumamoto-u.ac.jp.

PMID: 30395845
DOI: 10.1016/j.jid.2018.09.030

No abstract available

Publication types

Letter

MeSH terms

Carcinoma, Squamous Cell / genetics*
Carcinoma, Squamous Cell / metabolism
Carcinoma, Squamous Cell / pathology
Cell Line, Tumor
Cell Movement
Cell Proliferation
Gene Expression Regulation, Neoplastic*
Gene Fusion / genetics
Humans
Intracellular Signaling Peptides and Proteins / biosynthesis
Intracellular Signaling Peptides and Proteins / genetics*
Protein Kinases / biosynthesis
Protein Kinases / genetics*
RNA, Neoplasm / genetics
Skin Neoplasms / genetics*
Skin Neoplasms / metabolism
Skin Neoplasms / pathology

Substances

Intracellular Signaling Peptides and Proteins
NUMBL protein, human
RNA, Neoplasm
COQ8B protein, human
Protein Kinases