Towards the targeted management of hereditary gingival fibromatosis

Med Hypotheses. 2018 Dec:121:188-190. doi: 10.1016/j.mehy.2018.09.017. Epub 2018 Sep 10.

Abstract

Although hereditary gingival fibromatosis is a rare condition, it leaves unrestroable psychological, esthetical as well as functional problems to the affected patients. The purpose of the current research is to find a non-surgical pharmacological mechanism that could provide a control of the active phase of such disease helping individual to continue their lives.

Keywords: Calcium; Connective tissue; Epithelium; Gingival fibromatosis; Vitamin D.

MeSH terms

  • Calcium / metabolism
  • Connective Tissue
  • Epithelium / metabolism*
  • Fibromatosis, Gingival / therapy*
  • Gingiva / pathology*
  • Hepatocyte Growth Factor / metabolism
  • Homeostasis
  • Humans
  • Insulin-Like Growth Factor I / metabolism
  • Periodontal Diseases / pathology
  • Vitamin D / metabolism

Substances

  • Vitamin D
  • Hepatocyte Growth Factor
  • Insulin-Like Growth Factor I
  • Calcium

Supplementary concepts

  • Fibromatosis, Gingival, Hereditary