Surface modification of chitosan films with a fibronectin fragment-DNA aptamer complex to enhance osteoblastic cell activity: A mass spectrometry approach probing evidence on protein behavior

Rapid Commun Mass Spectrom. 2019 Feb 28;33(4):336-342. doi: 10.1002/rcm.8335.

Authors

Martina Saccani¹, Ludovica Parisi^{2

3}, Carlo Bergonzi¹, Annalisa Bianchera⁴, Carlo Galli^{2

3}, Guido Maria Macaluso^{2

3}, Ruggero Bettini¹, Lisa Elviri¹

Affiliations

¹ Department of Food and Drug Science, University of Parma, Parco Area delle Scienze 27/A, 43124, Parma, Italy.
² Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, Parma, Italy.
³ Centro Universitario di Odontoiatria, University of Parma, Via Gramsci 14, 43126, Parma, Italy.
⁴ Interdepartmental Centre Biopharmanet-Tec, University of Parma Parco, Area delle Scienze 27/A, 43124, Parma, Italy.

PMID: 30398689
DOI: 10.1002/rcm.8335

No abstract available

MeSH terms

Animals
Aptamers, Nucleotide / chemistry*
Aptamers, Nucleotide / metabolism
Cell Adhesion
Cell Proliferation
Chitosan / chemistry*
Fibronectins / chemistry*
Fibronectins / metabolism
Mass Spectrometry
Mice
Osteoblasts / chemistry
Osteoblasts / cytology*
Osteoblasts / metabolism
Tissue Scaffolds / chemistry*

Substances

Aptamers, Nucleotide
Fibronectins
Chitosan