Understanding and repurposing CRISPR-mediated alternative splicing

Genome Biol. 2018 Nov 6;19(1):184. doi: 10.1186/s13059-018-1565-3.

Abstract

Two new studies refine our understanding of CRISPR-associated exon skipping and redefine its utility in engineering alternative splicing.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alternative Splicing*
  • CRISPR-Cas Systems*
  • Exons*
  • Gene Editing / methods*
  • Humans
  • RNA, Guide / genetics*

Substances

  • RNA, Guide