Menstrual Cycle Changes as Women Approach the Final Menses: What Matters?

Obstet Gynecol Clin North Am. 2018 Dec;45(4):599-611. doi: 10.1016/j.ogc.2018.07.003. Epub 2018 Oct 25.

Abstract

Increased variability in menstrual cycle length marks the onset of the menopausal transition, with the likelihood of long cycles increasing as women approach menopause. This article describes the STRAW+10 bleeding criteria for recognizing onset of the early and late menopausal transition, as well as the specific bleeding changes a woman may experience during this life stage, including how women's bleeding experiences differ. The high probability of episodes of excessive and prolonged bleeding as women approach their final menstrual period is documented, as is the continuing probability of ovulation as women reach their final menstrual period.

Keywords: Abnormal uterine bleeding; Menopausal transition; Menopause; Menstruation.

Publication types

  • Review

MeSH terms

  • Anovulation / physiopathology
  • Female
  • Follicle Stimulating Hormone / blood
  • Follicular Phase / physiology*
  • Humans
  • Luteinizing Hormone / blood
  • Menopause / physiology*
  • Menstrual Cycle / physiology*
  • Ovulation / physiology
  • Progesterone / blood
  • Reproductive Health*
  • Women's Health*

Substances

  • Progesterone
  • Luteinizing Hormone
  • Follicle Stimulating Hormone