Headache in challenging and special circumstances: Pregnancy and lactation

Agri. 2018 Oct;30(4):153-164. doi: 10.5505/agri.2018.85688.


Headache has special importance during pregnancy and postpartum period. The health-care professionals and patients report headache management as challenging during pregnancy and lactation period. Cautions are recommended in preganancy and lactation due to maternal and fetal/newborn risks. Most headaches in the first trimester are due primary headaches. Nevertheless, the incidence of secondary headaches increase in the last trimester and post-partum period. Red flags prompt early evaluation in a patient with headache. Assessment of headache patient requires a detailed history of the headache characteristics and performing appropriate examinations. Approach to headache and strategies to promote best practice in preganancy and lactation will be reviewed.

Publication types

  • Review

MeSH terms

  • Analgesics / adverse effects
  • Analgesics / therapeutic use
  • Female
  • Headache / drug therapy*
  • Humans
  • Lactation*
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Prenatal Diagnosis*
  • Puerperal Disorders / drug therapy*


  • Analgesics