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. 2018 Dec;69(12):1006-1013.
doi: 10.1007/s00105-018-4300-9.

[Sexually Transmitted Infections and Male Fertility]

[Article in German]

[Sexually Transmitted Infections and Male Fertility]

[Article in German]
P Spornraft-Ragaller et al. Hautarzt. .


Background: Sexually transmitted infections (STI) are common worldwide and can cause impairment of fertility. In women pelvic inflammatory disease with subsequent tubal sterility is well-documented but the influence of STI on male fertility is still controversely discussed OBJECTIVE: The effects of various bacterial and viral STI on male fertility are discussed.

Material and methods: An evaluation of the international literature up to 30 April 2018 was carried out including studies on larger collectives from the Asiatic region.

Results: There is still an inconsistent picture of the influence of various bacterial and viral STI on male fertility. Direct or indirect evidence of the impact of a pathogen alone on the quality of ejaculates could not be clearly demonstrated; however, there are indications of a negative effect by Mycoplasma and Ureaplasma species in large Asiatic collectives. The transmission of viral pathogens, such as human papillomavirus (HPV), herpes simplex virus (HSV) and hepatitis B virus (HBV) possible impairs the success of assisted reproductive techniques. In contrast, manifest inflammatory processes of the male genital tract caused by STI (in particular Chlamydia and gonococci) or human immunodeficiency virus (HIV) infections often result in impairment of sperm qualtity.

Conclusion: In cases of male fertility disorders a microbiological clarification is recommended. Further studies on the effect of STI on male fertility in larger collectives are necessary, particularly for Caucasian populations. The utilization of existing preventive measures, such as screening for Chlamydia in young women and HPV vaccination also for young males, should be intensively promoted.

Keywords: Bacteria; Male fertility; STI; Sperm quality; Viruses.

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