Health maintenance for adults with neuromuscular diseases on immunosuppression

Muscle Nerve. 2019 Apr;59(4):397-403. doi: 10.1002/mus.26382. Epub 2018 Dec 21.

Abstract

Immunosuppressants are commonly used in the treatment of neuromuscular diseases. The use of these medications requires health maintenance screening and monitoring for multiple potential sides effects, which may be best conducted when the prescribing physician and primary care physician work in tandem. Clinical practice guidelines, recommendations from professional organizations, prescription drug labeling, and expert opinion were reviewed and combined to provide recommendations for health maintenance for eight different immunosuppressants. Recommendations are provided for vaccinations, infection prophylaxis, laboratory monitoring, bone density screening, cancer screening, and other considerations. While studies in individuals with neuromuscular diseases are sparse, knowledge gained from the use of immunosuppressants in other conditions is applied in this review to provide recommendations to be used during the treatment of neuromuscular diseases in adults. Muscle Nerve 59:397-403, 2019.

Keywords: cancer screening; immunosuppression; infection prophylaxis; neuromuscular disease; osteoporosis; vaccines.

Publication types

  • Review

MeSH terms

  • Health Status
  • Humans
  • Immunosuppression Therapy
  • Immunosuppressive Agents / adverse effects*
  • Immunosuppressive Agents / therapeutic use*
  • Neuromuscular Diseases / complications*
  • Neuromuscular Diseases / therapy*
  • Vaccination

Substances

  • Immunosuppressive Agents