Evolving Role of PET/CT-MRI in Assessing Muscle Disorders

Esha Kothekar; William Y Raynor; Abdullah Al-Zaghal; Venkata S Jonnakuti; Thomas J Werner; Abass Alavi

doi:10.1016/j.cpet.2018.08.010

Evolving Role of PET/CT-MRI in Assessing Muscle Disorders

PET Clin. 2019 Jan;14(1):71-79. doi: 10.1016/j.cpet.2018.08.010. Epub 2018 Oct 24.

Authors

Esha Kothekar¹, William Y Raynor², Abdullah Al-Zaghal¹, Venkata S Jonnakuti³, Thomas J Werner¹, Abass Alavi⁴

Affiliations

¹ Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
² Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA; Department of Radiology, Drexel University College of Medicine, 230 N Broad Street, Philadelphia, PA 19102, USA.
³ Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA; 1 Baylor Plaza, Houston, TX 77030, USA.
⁴ Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: abass.alavi@uphs.upenn.edu.

PMID: 30420223
DOI: 10.1016/j.cpet.2018.08.010

Abstract

2-Deoxy-2-[¹⁸F]fluoroglucose (FDG) uptake in muscle is influenced by many normal physiologic processes and can also indicate pathology. Variability in physiologic uptake can be reduced with proper patient preparation, allowing for a better determination of abnormal activity. Although malignant diseases, such as rhabdomyosarcoma and skeletal muscle metastasis, are clear applications of FDG-PET/CT, there may be additional applications in infection and benign inflammatory disorders that warrant further research.

Keywords: FDG; Inflammatory muscle disorders; Muscle disorders; Musculoskeletal malignancies; PET/CT-MRI.

Publication types

Review

MeSH terms

Humans
Magnetic Resonance Imaging / methods*
Multimodal Imaging / methods*
Muscle, Skeletal / diagnostic imaging
Muscular Diseases / diagnostic imaging*
Positron Emission Tomography Computed Tomography / methods*