Pre-Processing MALDI/TOF Mass Spectra by Using Geena 2

P Romano; A Profumo; A Facchiano

doi:10.1002/cpbi.59

Pre-Processing MALDI/TOF Mass Spectra by Using Geena 2

Curr Protoc Bioinformatics. 2018 Dec;64(1):e59. doi: 10.1002/cpbi.59. Epub 2018 Nov 13.

Authors

P Romano¹, A Profumo¹, A Facchiano²

Affiliations

¹ Ospedale Policlinico San Martino, Ospedale Policlinico San Martino, Genoa, Italy.
² CNR-Istituto di Scienze dell'Alimentazione, Avellino, Italy.

PMID: 30422396
DOI: 10.1002/cpbi.59

Abstract

Geena 2 is a tool for filtering, averaging, and aligning MALDI/TOF mass spectra, designed to assist scientists in the analysis of high volumes of data and support them for comparative studies. Three web interfaces are available with different levels of complexity. In this manuscript, we explain how to use Geena 2 with these three interfaces to perform analyses of one's own data. Two support protocols showing how to check the example input file and how to create an input file with own data are also presented. © 2018 by John Wiley & Sons, Inc.

Keywords: MALDI/TOF; mass spectrometry; pre-processing; spectra alignment.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Guidelines as Topic
Software*
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods*
User-Computer Interface

Abstract

Publication types

MeSH terms

Grants and funding