Caffeine Toxicity

Excerpt

Caffeine is a stimulant that has been used globally for centuries due to its ability to improve mental alertness. Approximately 85% of Americans consume caffeine daily, with an average cup of coffee containing between 40 and 150 mg of caffeine. Caffeine can be found in various over-the-counter products, such as energy drinks, appetite suppressants, stimulants, exercise supplements, decongestants, bronchodilators, and mental stimulants, increasing the risk of toxicity with inadvertent overuse or severe toxicity with an intentional overdose.

Lethal doses of caffeine have been reported at blood concentrations of 80 to 100 μg/mL, which can result from ingesting approximately 10 g or more of caffeine.