Lymphocyte Changes in Acute Malaria

Trans R Soc Trop Med Hyg. 1977;71(5):408-10. doi: 10.1016/0035-9203(77)90039-6.


Lymphocyte sub-populations were studied in children with acute malaria. Depletion of T cells was found associated with an increased proportion of null cells. K cell activity for chicken red cells was also increased and it is likely that some of the increased number of null cells were K cells. An increase in K cell activity in acute malaria could be part of a protective immune response.

MeSH terms

  • Antibody-Dependent Cell Cytotoxicity
  • B-Lymphocytes
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Killer Cells, Natural
  • Leukocyte Count
  • Lymphocytes*
  • Malaria / immunology*
  • T-Lymphocytes