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. 2018 Nov 14;22(1):296.
doi: 10.1186/s13054-018-2227-2.

Selective Decontamination of the Digestive Tract in Critical Care: A Teenage Angst or Coming of Age Issue?

Free PMC article

Selective Decontamination of the Digestive Tract in Critical Care: A Teenage Angst or Coming of Age Issue?

Brian H Cuthbertson. Crit Care. .
Free PMC article


Selective decontamination of the digestive tract (SDD) has been with us since the early days of our specialty, and in some ways it marks our progression and maturation. How we have dealt with SDD to date ranges from "thorn in our side" to "elephant in the room". With high quality multi-national studies underway, how we deal with these results will mark our final maturation to adulthood as a specialty.

Keywords: Antibiotics; Evidence; Prevention; Selective decontamination of the digestive tract; Sepsis.

Conflict of interest statement

Authors’ information

Dr. Cuthbertson is Chief and Professor of Critical Care Medicine at Sunnybrook Health Sciences Centre and the University of Toronto.

Ethics approval and consent to participate

No ethical approval was sought as this is an editorial comment.

Consent for publication

I consent for publication of this article in Critical Care.

Competing interests

I am the principal investigator of the SuDDICU study, a multi-national RCT of SDD in critical illness.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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