TachoSil Dural Reconstruction in Extracranial-Intracranial Bypass Surgeries

J Neurol Surg A Cent Eur Neurosurg. 2019 Jan;80(1):39-43. doi: 10.1055/s-0038-1675565. Epub 2018 Nov 15.

Abstract

Background: Superficial temporal artery to middle cerebral artery (STA-MCA) bypass is a treatment option for hemodynamic insufficiency in the anterior cerebral circulation. Complications associated with extracranial-intracranial bypass surgeries are ischemic strokes caused by bypass failure, wound-healing disorders, and further issues from cerebrospinal fluid (CSF) leakage. CSF leakage can provide pathways for infection. It is well known in general neurosurgery that watertight closure of the dura mater is necessary to prevent such complications.

Objective: To provide a technical description of TachoSil dural reconstruction in standard STA-MCA bypasses and their follow-up analyses.

Methods: In this technical report with observational follow-up, the dura mater was closed partially by adaptive sutures, and the perforation site of the donor vessel was sealed with TachoSil. TachoSil is a collagen sponge covered with clotting factors that provides hemostatic and sealing effects.

Results: Our study included eight cases of standard STA-MCA bypasses that had been operated between July 2015 and September 2016. Follow-up examinations were completed for all patients at 1 month and 6 months after surgery. Duplex and Doppler ultrasound demonstrated regular bypass patency in all patients without increased flow velocity at the perforation sites, which is a possible sign of stenosis. No wound-healing disorders or CSF leakage occurred. No cerebrovascular stroke events were observed.

Conclusion: Duraplasty with TachoSil enables the elastic reconstruction of the dura perforation gap in standard extracranial-intracranial bypass surgeries.

Publication types

  • Observational Study

MeSH terms

  • Brain Ischemia / etiology
  • Brain Ischemia / pathology
  • Brain Ischemia / surgery*
  • Cerebral Revascularization*
  • Cerebrospinal Fluid Leak / etiology
  • Cerebrospinal Fluid Leak / prevention & control
  • Drug Combinations
  • Dura Mater / surgery*
  • Fibrinogen / therapeutic use*
  • Humans
  • Middle Cerebral Artery / surgery
  • Plastic Surgery Procedures / adverse effects
  • Plastic Surgery Procedures / methods*
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control
  • Stroke / etiology
  • Stroke / prevention & control
  • Temporal Arteries / surgery
  • Thrombin / therapeutic use*

Substances

  • Drug Combinations
  • TachoSil
  • Fibrinogen
  • Thrombin