Asbestos exposure and gastrointestinal malignancy review and meta-analysis

Am J Ind Med. 1988;14(1):79-95. doi: 10.1002/ajim.4700140110.


The epidemiologic literature linking asbestos exposure with gastrointestinal malignancy is reviewed. Problems in comparing studies are discussed, appropriate strategies for comparison are developed, and study results are pooled using a model which accounts for both intrastudy and interstudy variability. Stratification of cohorts by dose reveals that significant asbestos exposure, as indicated by a lung cancer standardized mortality ratio (SMR) of at least 200, is associated with an elevated gastrointestinal cancer of SMR for five of six points examined [corrected].

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Asbestos / adverse effects*
  • Gastrointestinal Neoplasms / etiology*
  • Humans
  • Occupational Diseases / etiology*
  • Research Design


  • Asbestos