Metal Oxide Nanoparticle Based Electrochemical Sensor for Total Antioxidant Capacity (TAC) Detection in Wine Samples

Biosensors (Basel). 2018 Nov 14;8(4):108. doi: 10.3390/bios8040108.


A single-use electrochemical screen-printed electrode is reported based on biomimetic properties of nanoceria particles (CeNPs). The developed tool showed an easy approach compared to the classical spectrophotometric methods reported in literature in terms of ease of use, cost, portability, and unnecessary secondary reagents. The sensor allowed the detection of the total antioxidant capacity (TAC) in wine samples. The sensor has been optimized and characterized electrochemically and then tested with antioxidant compounds occurred in wine samples. The electrochemical CeNPs modified sensor has been used for detection of TAC in white and red commercial wines and the data compared to the 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid (ABTS)-based spectrophotometric method. Finally, the obtained results have demonstrated that the proposed sensor was suitable for the simple and quick evaluation of TAC in beverage samples.

Keywords: SPE sensor; antioxidants; disposable sensor; enzyme mimetic; nanoceria; total antioxidant capacity; wine.

MeSH terms

  • Antioxidants / chemistry*
  • Electrochemistry / methods*
  • Metal Nanoparticles / chemistry*
  • Spectrophotometry
  • Wine


  • Antioxidants