Genetic Testing and Counseling for Hypertrophic Cardiomyopathy

Allison L Cirino; Christine E Seidman; Carolyn Y Ho

doi:10.1016/j.ccl.2018.08.003

Genetic Testing and Counseling for Hypertrophic Cardiomyopathy

Cardiol Clin. 2019 Feb;37(1):35-43. doi: 10.1016/j.ccl.2018.08.003. Epub 2018 Oct 29.

Authors

Allison L Cirino¹, Christine E Seidman², Carolyn Y Ho³

Affiliations

¹ Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
² Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA; Department of Genetics, Harvard Medical School, NRB 256, 77 Avenue Louis Pasteur, Boston, MA 02115, USA; Howard Hughes Medical Institute, HHMI Investigator Program, 4000 Jones Bridge Road, Chevy Chase, MD 20815, USA.
³ Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Electronic address: cho@bwh.harvard.edu.

PMID: 30447714
DOI: 10.1016/j.ccl.2018.08.003

Abstract

Genetic testing has become more accessible and is increasingly being incorporated into the care of patients with hypertrophic cardiomyopathy. Genetic test results can help to refine diagnosis and distinguish at-risk relatives from those who are not at risk.

Keywords: Genetic counseling; Genetic testing; Hypertrophic cardiomyopathy; Pedigree.

Publication types

Review

MeSH terms

Cardiomyopathy, Hypertrophic / diagnosis*
Cardiomyopathy, Hypertrophic / genetics
Communication
Early Diagnosis
Female
Genetic Counseling / methods*
Genetic Testing / methods*
Humans
Male
Patient Care Team
Patient Selection
Pedigree