Comorbidity of Borderline Personality Disorder: Current Status and Future Directions

Ravi Shah; Mary C Zanarini

doi:10.1016/j.psc.2018.07.009

Comorbidity of Borderline Personality Disorder: Current Status and Future Directions

Psychiatr Clin North Am. 2018 Dec;41(4):583-593. doi: 10.1016/j.psc.2018.07.009. Epub 2018 Oct 16.

Authors

Ravi Shah¹, Mary C Zanarini²

Affiliations

¹ Laboratory for the Study of Adult Development, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA.
² Laboratory for the Study of Adult Development, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA. Electronic address: zanarini@mclean.harvard.edu.

PMID: 30447726
DOI: 10.1016/j.psc.2018.07.009

Abstract

Patients with borderline personality disorder have high rates of comorbid mood, anxiety, substance use, and eating disorders. The longitudinal studies conducted on borderline patients over 10 years of prospective follow-up suggest that patients with borderline personality disorder experienced declining rates of Axis I disorders over time, but the rates of these disorders remained high compared with those with other personality disorders. In addition, patients whose borderline personality disorder remitted over time experienced a substantial decline in all comorbid Axis I disorders, but those whose borderline personality disorder did not remit over time, reported stable rates of comorbid disorders.

Keywords: Axis I disorders; BPD; Comorbidity; New onset; Prevalence; Recurrence; Remission.

Publication types

Review

MeSH terms

Anxiety Disorders / epidemiology*
Borderline Personality Disorder / diagnosis
Borderline Personality Disorder / epidemiology*
Comorbidity*
Humans
Mood Disorders / diagnosis
Mood Disorders / epidemiology*
Prospective Studies
Substance-Related Disorders / epidemiology