The Challenges of Approaching and Managing Gout

Rheum Dis Clin North Am. 2019 Feb;45(1):145-157. doi: 10.1016/j.rdc.2018.09.009.

Abstract

Despite many effective treatments for gout, its management remains a challenge internationally. Options for optimizing gout management may differ in different practice sizes and settings. Gout incidence is rising and it continues to be associated with increased mortality. Education of patients and medical providers is essential, and newer gout medications need to be used in the most appropriate ways for cost-effective therapy. Special consideration needs to be given to such populations as the elderly and those with renal and cardiovascular disease in gout management. New agents are in development, which may add to the armamentarium for gout management.

Keywords: Gout; Gouty arthritis; Patient education; Physician education.

Publication types

  • Review

MeSH terms

  • Acetamides / therapeutic use
  • Allopurinol / therapeutic use
  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Colchicine / therapeutic use
  • Diet Therapy*
  • Febuxostat / therapeutic use
  • Gout / blood
  • Gout / diagnosis
  • Gout / therapy*
  • Gout Suppressants / therapeutic use*
  • Humans
  • Medication Adherence*
  • Patient Education as Topic*
  • Phenylacetates / therapeutic use
  • Polyethylene Glycols / therapeutic use
  • Quality of Health Care
  • Rheumatology
  • Thioglycolates / therapeutic use
  • Triazoles / therapeutic use
  • Urate Oxidase / therapeutic use
  • Uric Acid / blood

Substances

  • Acetamides
  • Antibodies, Monoclonal, Humanized
  • Gout Suppressants
  • Phenylacetates
  • Thioglycolates
  • Triazoles
  • lesinurad
  • Febuxostat
  • arhalofenate
  • Uric Acid
  • canakinumab
  • Polyethylene Glycols
  • Allopurinol
  • Urate Oxidase
  • Pegloticase
  • Colchicine