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Review
. 2019 Jan;35(1):61-73.
doi: 10.1016/j.ccc.2018.08.009. Epub 2018 Oct 25.

Renal Complications Following Lung Transplantation and Heart Transplantation

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Review

Renal Complications Following Lung Transplantation and Heart Transplantation

Chethan M Puttarajappa et al. Crit Care Clin. .

Abstract

Renal complications are common following heart and/or lung transplantation and lead to increased morbidity and mortality. Renal dysfunction is also associated with increased mortality for patients on the transplant wait list. Dialysis dependence is a relative contraindication for heart or lung transplantation at most centers, and such patients are often listed for a simultaneous kidney transplant. Several factors contribute to the impaired renal function in patients undergoing heart and/or lung transplantation, including the interplay between cardiopulmonary and renal hemodynamics, complex perioperative issues, and exposure to nephrotoxic medications, mainly calcineurin inhibitors.

Keywords: Acute kidney injury; Continuous renal replacement therapy; Dialysis; Heart transplantation; Lung transplantation.

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