Delayed Allergic Reaction to ChloraPrepTM in Foot and Ankle Surgery

J Foot Ankle Surg. 2019 Jan;58(1):192-194. doi: 10.1053/j.jfas.2018.08.019. Epub 2018 Nov 15.

Abstract

Chlorhexidine-based skin preparations are frequently used in orthopaedic surgery. We report 2 recent cases of patients suffering significant allergic reactions to ChloraPrepTM complicating routine foot and ankle surgery. We advise vigilance for this possible issue and recommend thorough removal of all preparation at the end of the procedure.

Keywords: allergy; chlorhexidine; rash; surgical preparation; surgical safety.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Anti-Infective Agents, Local / adverse effects*
  • Chlorhexidine / adverse effects*
  • Drug Hypersensitivity / diagnosis*
  • Drug Hypersensitivity / etiology
  • Female
  • Humans
  • Hypersensitivity, Delayed / chemically induced*
  • Hypersensitivity, Delayed / diagnosis*
  • Male
  • Orthopedic Procedures*
  • Preoperative Care

Substances

  • Anti-Infective Agents, Local
  • Chlorhexidine