Nitroxoline: an option for the treatment of urinary tract infection with multi-resistant uropathogenic bacteria

Herbert Hof; C Juretschke

doi:10.1007/s15010-018-1253-y

Nitroxoline: an option for the treatment of urinary tract infection with multi-resistant uropathogenic bacteria

Infection. 2019 Jun;47(3):493-495. doi: 10.1007/s15010-018-1253-y. Epub 2018 Nov 17.

Authors

Herbert Hof¹, C Juretschke²

Affiliations

¹ MVZ Labor Limbach und Kollegen, Im Breitspiel 16, 69126, Heidelberg, Germany. herbert.hof@labor-limbach.de.
² Department of Pneumology, Theresienkrankenhaus, Bassermannstr. 1, 68165, Mannheim, Germany.

PMID: 30449013
DOI: 10.1007/s15010-018-1253-y

Abstract

The number of multi-resistant uropathogens is increasing. A multi-morbid patient developed a symptomatic urinary tract infection with two multi-resistant bacteria, namely Klebsiella pneumoniae and Proteus mirabilis. Nitroxoline was the only drug active against both uropathogens. Obviously, nitroxoline can be an option for the therapy of a urinary tract infection with multi-resistant uropathogens.

Keywords: Multi-resistant uropathogens; Nitroxoline; Urinary tract infections.

Publication types

Case Reports

MeSH terms

Aged
Anti-Bacterial Agents / therapeutic use*
Drug Resistance, Multiple, Bacterial*
Germany
Humans
Klebsiella Infections / drug therapy
Klebsiella Infections / microbiology
Klebsiella pneumoniae / drug effects*
Male
Microbial Sensitivity Tests
Nitroquinolines / therapeutic use*
Proteus Infections / drug therapy
Proteus Infections / microbiology
Proteus mirabilis / drug effects*
Serbia
Urinary Tract Infections / drug therapy*
Urinary Tract Infections / microbiology

Substances

Anti-Bacterial Agents
Nitroquinolines
nitroxoline