Keywords: CR, complete response; CT, computed tomography; FDA, US Food and Drug Administration; MCC, Merkel cell carcinoma; Merkel cell carcinoma; PD-1, programmed cell death protein-1; PD-L1, programmed death ligand-1; PR, partial response; TVEC, talimogene laherparepvec; pembrolizumab; programmed cell death-1; programmed death ligand-1; talimogene laherparepvec.