Symptom Science Research in the Era of Big Data: Leveraging Interdisciplinary Resources and Partners to Make It Happen

J Nurs Scholarsh. 2019 Jan;51(1):4-8. doi: 10.1111/jnu.12446. Epub 2018 Nov 19.


Purpose: The purpose of this article is to review the concept of team science as well as its benefits and challenges, within the framework of how including new ways of knowing can advance nursing science.

Design: An exemplar highlights the experiences and strategies utilized by researchers at one school of nursing as they increasingly became involved in team science.

Methods: Presented are the steps and processes that occurred as team science became the norm, expanding to include a network of linked investigators.

Conclusions: Although challenges to conducting team science exist, a reflection on how team science fits into the theoretical framework of Carper's Patterns of Knowing highlights its potential to drive nursing research forward.

Clinical relevance: Leading or participating in team science can expand the lens by which nursing scientists conduct research that is meaningful to patients and families.

Keywords: Chronic stress; exposome; glucocorticoid resistance; metabolomics; microbiome; preterm birth; team science.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • African Americans
  • Algorithms
  • Big Data*
  • Ethnic Groups
  • Female
  • Humans
  • Interdisciplinary Communication
  • Interdisciplinary Research*
  • Knowledge
  • Microbiota
  • Models, Theoretical
  • Nursing Research / methods*
  • Nursing Research / organization & administration*
  • Pregnancy
  • Pregnancy Outcome
  • Prenatal Care
  • RNA, Ribosomal, 16S / metabolism
  • Risk
  • Stress, Psychological
  • Symptom Assessment / methods*


  • RNA, Ribosomal, 16S