Fluorinated Alcohol-Promoted Reaction of Chlorohydrocarbons with Diverse Nucleophiles for the Synthesis of Triarylmethanes and Tetraarylmethanes

Liping Yu; Shuai-Shuai Li; Weina Li; Shitao Yu; Qing Liu; Jian Xiao

doi:10.1021/acs.joc.8b02549

Fluorinated Alcohol-Promoted Reaction of Chlorohydrocarbons with Diverse Nucleophiles for the Synthesis of Triarylmethanes and Tetraarylmethanes

J Org Chem. 2018 Dec 21;83(24):15277-15283. doi: 10.1021/acs.joc.8b02549. Epub 2018 Dec 6.

Authors

Liping Yu¹, Shuai-Shuai Li², Weina Li², Shitao Yu¹, Qing Liu³, Jian Xiao²

Affiliations

¹ College of Chemical Engineering , Qingdao University of Science and Technology , Qingdao 266042 , China.
² Shandong Province Key Laboratory of Applied Mycology, College of Chemistry and Pharmaceutical Sciences , Qingdao Agricultural University , Qingdao 266109 , China.
³ College of Chemical and Environmental Engineering , Shandong University of Science and Technology , Qingdao 266590 , China.

PMID: 30450905
DOI: 10.1021/acs.joc.8b02549

Abstract

This article reports an efficient synthesis of triarylmethanes and tetraarylmethanes from chlorohydrocarbons with miscellaneous nucleophiles in fluorinated alcohols, featuring metal-free, wide substrate scope, excellent functional group tolerance, and mild reaction conditions.

Publication types

Research Support, Non-U.S. Gov't