The correlation between body mass index and prostatic-related parameters in men 40 years or older in Zhengzhou

Aging Male. 2020 Dec;23(5):483-488. doi: 10.1080/13685538.2018.1530754. Epub 2018 Nov 17.

Abstract

Purpose: To understand the relationship between body mass index (BMI), age, prostate volume (PV), prostate-specific antigen (PSA), International Prostate Symptom Score (IPSS) and quality of life (QoL) in Zhengzhou.

Materials and methods: In the cross-sectional study, men living in Zhengzhou were invited to participate in this study. Men who were 40 years or older were subjected to the IPSS and related examination. A total of 1360 participants were included. Body mass index < 18.5 kg/m2 was determined as underweight, 18.5-24.99 kg/m2 normal, 25-29.99 kg/m2 overweight, and ≥30 kg/m2 obese.

Results: The mean BMI was 24.92 ± 3.37 kg/m2. The mean PSA was 1.06 ± 0.85 ng/mL. The mean PV was 20.10 ± 9.96 mL. The mean age was 62.72 ± 11.03 years. The mean IPSS was 5.87 ± 3.48 scores. The mean QoL was 2.33 ± 1.28 scores. PSA showed a significant tendency to decrease with increasing BMI (r = -0.061, p = 0.018, ptrend = 0.037). The same with age (r = -0.109, p < .001; ptrend = .045). But the result suggested that both IPSS and QoL were positively correlated with BMI (r = 0.120, p < .001, ptrend < .001; r = 0.083, p = .001, ptrend = .021, respectively). PV increased with increasing BMI (r = 0.110, p < .001, ptrend = 0.045 ).

Conclusions: Age, PSA decreased with increasing BMI. But larger PV, IPSS, and QoL were associated with higher BMI.

Keywords: Body mass index; lower urinary tract symptoms; prostate volume; prostate-specific antigen.

MeSH terms

  • Aged
  • Body Mass Index
  • Cross-Sectional Studies
  • Humans
  • Male
  • Middle Aged
  • Prostate-Specific Antigen
  • Prostatic Hyperplasia*
  • Quality of Life*

Substances

  • Prostate-Specific Antigen