Disseminated cryptococcosis in a HIV-negative patient: Case report of a newly diagnosed hypertensive adult presenting with hemiparesis

Raymond M Wilson; Nyambura Moremi; Martha F Mushi; Oliver Bader; Patrick S Ngoya; Bernard M Desderius; Peter Rambau; Rodrick Kabangila; Uwe Groß; Stephen E Mshana

doi:10.1016/j.mmcr.2018.07.003

Disseminated cryptococcosis in a HIV-negative patient: Case report of a newly diagnosed hypertensive adult presenting with hemiparesis

Med Mycol Case Rep. 2018 Jul 12:22:4-7. doi: 10.1016/j.mmcr.2018.07.003. eCollection 2018 Dec.

Authors

Affiliations

¹ Department of Internal Medicine, Bugando Medical Centre/Catholic University of Health and Allied Science, Mwanza, Tanzania.
² Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
³ Institute of Medical Microbiology, University Medical Center Goettingen, Germany.
⁴ Department of Radiology, Bugando Medical Centre, Mwanza, Tanzania.
⁵ Department of Pathology, Weill Bugando School of Medicine, Mwanza, Tanzania.
⁶ Kamanga Medics Hospital, Mwanza, Tanzania.

Abstract

We report a case of disseminated cryptococcosis in a 42-year old immunocompetent female. Prior to admission at Bugando Medical Center, the patient was attended at three hospitals for hypertension and clinically diagnosed malaria. Following diagnosis of disseminated Cryptococcus at our center, she was successfully treated with fluconazole but remained with visual loss. Blood cultures should be considered in the management of any adult presenting with fever to enable early detection of the least expected differentials like in this case.

Keywords: C. gattii; Cryptococcus deuterogattii; Disseminated cryptococcosis; HIV negative; Meningism.

Publication types

Case Reports