Clinical Review Report: Migalastat (Galafold): (Amicus Therapeutics) [Internet]

Review
Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2018 Feb.

Excerpt

The objective of this report was to perform a systematic review of the beneficial and harmful effects of migalastat 123 mg capsule (equivalent to 150 mg migalastat hydrochloride [HCl]) for long-term treatment of adults with a confirmed diagnosis of Fabry disease (FD) (deficiency of alpha-Gal A) and who have an alpha-galactosidase A (alpha-Gal A) mutation determined to be amenable by an in vitro assay.

Publication types

  • Review

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