Placebo response in panic disorder

Am J Psychiatry. 1988 Sep;145(9):1138-40. doi: 10.1176/ajp.145.9.1138.

Abstract

Of 43 patients with panic disorder or agoraphobia with panic attacks who took placebo for 8 weeks in two double-blind studies, one in four markedly improved. Those with consistently normal dexamethasone suppression test results were significantly more likely to show a placebo response as were those with lower anxiety ratings at the outset of treatment.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Agoraphobia / drug therapy
  • Alprazolam / therapeutic use
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / drug therapy*
  • Anxiety Disorders / psychology
  • Clinical Trials as Topic
  • Dexamethasone
  • Diazepam / therapeutic use
  • Double-Blind Method
  • Fear*
  • Female
  • Humans
  • Hydrocortisone / blood
  • Male
  • Panic*
  • Placebos / therapeutic use*
  • Psychiatric Status Rating Scales

Substances

  • Placebos
  • Dexamethasone
  • Diazepam
  • Hydrocortisone
  • Alprazolam