Outcome after reconstruction of proximal femoral tumors: A systematic review

J Surg Oncol. 2019 Jan;119(1):120-129. doi: 10.1002/jso.25297. Epub 2018 Nov 22.


Tumor resection followed by reconstruction with a proximal femoral endoprosthesis or an allograft-prosthesis composite are the two main alternatives for treatment of proximal femoral malignancies. This review describes the revision rate, implant survival, limb salvage rate, and function. Overall revision rates are high and reasons for failure differ between treatment modalities. Rate and reasons for amputation are comparable between both methods. Functional outcome was reasonable to good on average for both treatment modalities. Level of evidence: IV, systematic review and meta-analysis.

Keywords: allograft; benign; cancer; femoral; femur; malignant; prosthesis; proximal; reconstruction; replacement; tumor.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Femoral Neoplasms / pathology*
  • Femoral Neoplasms / surgery*
  • Humans
  • Reconstructive Surgical Procedures / methods*
  • Treatment Outcome