Atopic Dermatitis: New Developments

Dermatol Clin. 2019 Jan;37(1):11-20. doi: 10.1016/j.det.2018.07.003. Epub 2018 Nov 1.

Abstract

Herein we review recent developments in our understanding and treatment of atopic dermatitis. Key insights from the recent literature are summarized, from findings on the pathogenesis of this multifactorial disease to a new and more nuanced understanding of its natural history. Therapeutic advances and new data on comorbidities are also discussed.

Keywords: Atopic dermatitis; Comorbidities; Eczema; Pathogenesis; Prevention; Treatment.

Publication types

  • Review

MeSH terms

  • Antibodies, Monoclonal / therapeutic use
  • Antibodies, Monoclonal, Humanized
  • Baths
  • Boron Compounds / therapeutic use
  • Bridged Bicyclo Compounds, Heterocyclic / therapeutic use
  • Comorbidity
  • Dermatitis, Atopic / complications
  • Dermatitis, Atopic / drug therapy*
  • Dermatitis, Atopic / etiology*
  • Dermatitis, Atopic / physiopathology
  • Dermatologic Agents / therapeutic use
  • Environmental Exposure / adverse effects
  • Humans
  • Janus Kinase Inhibitors / therapeutic use
  • Pain / etiology
  • Patient Education as Topic
  • Peanut Hypersensitivity / prevention & control
  • Phosphodiesterase 4 Inhibitors / therapeutic use
  • Sodium Hypochlorite / therapeutic use

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Boron Compounds
  • Bridged Bicyclo Compounds, Heterocyclic
  • Dermatologic Agents
  • Janus Kinase Inhibitors
  • Phosphodiesterase 4 Inhibitors
  • dupilumab
  • Sodium Hypochlorite
  • crisaborole