Caution Is Required When Using Non-Food and Drug Administration-Cleared Assays to Diagnose Sexually Transmitted Infections in Children

Amanda D Brownell; Robert A Shapiro; Margaret R Hammerschlag

doi:10.1016/j.jpeds.2018.10.038

Caution Is Required When Using Non-Food and Drug Administration-Cleared Assays to Diagnose Sexually Transmitted Infections in Children

J Pediatr. 2019 Mar:206:280-282. doi: 10.1016/j.jpeds.2018.10.038. Epub 2018 Nov 19.

Authors

Amanda D Brownell¹, Robert A Shapiro², Margaret R Hammerschlag³

Affiliations

¹ Mayerson Center for Safe and Healthy Children, Cincinnati Children's Hospital, Cincinnati, OH. Electronic address: abrownell@spurwink.org.
² Mayerson Center for Safe and Healthy Children, Cincinnati Children's Hospital, Cincinnati, OH.
³ Department of Pediatrics, Division of Infectious Diseases, State University of New York, Downstate Medical Center, Brooklyn, NY.

PMID: 30466791
DOI: 10.1016/j.jpeds.2018.10.038

Abstract

Nucleic acid amplification testing is the gold-standard for Chlamydia trachomatis and Neisseria gonorrhoeae testing in adults. We present 3 pediatric cases in which testing resulted in probable false-positive results. Clinicians should avoid tests without clearance from a regulatory agency and should maintain consistent communication with laboratories.

Publication types

Case Reports

MeSH terms

Child
Child Abuse, Sexual / diagnosis
Child, Preschool
Diagnostic Test Approval
Female
Humans
Male
Nucleic Acid Amplification Techniques
Sensitivity and Specificity
Sexually Transmitted Diseases / diagnosis*
Sexually Transmitted Diseases / microbiology*