Connective Tissue Disorders in Pregnancy

Sophia L Ryan; Shamik Bhattacharyya

doi:10.1016/j.ncl.2018.09.006

Connective Tissue Disorders in Pregnancy

Neurol Clin. 2019 Feb;37(1):121-129. doi: 10.1016/j.ncl.2018.09.006.

Authors

Sophia L Ryan¹, Shamik Bhattacharyya²

Affiliations

¹ Department of Neurology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA; Department of Neurology, Massachusetts General Hospital, 75 Francis Street, Boston, MA 02115, USA; Department of Neurology, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address: sryan9@partners.org.
² Department of Neurology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA; Department of Neurology, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

PMID: 30470271
DOI: 10.1016/j.ncl.2018.09.006

Abstract

Connective tissue disorders are now understood to include autoimmune and genetic diseases affecting organs, blood vessels, and surrounding fascia. Many of these diseases predominantly affect women in childbearing years and are associated with neurologic complications. Pregnancy can affect disease activity (such as flares of systemic lupus erythematosus), and the diseases can affect pregnancy outcome (such as increased risk of preterm labor). We review the neurologic complications and changes with pregnancy for systemic lupus erythematosus, Sjögren syndrome, idiopathic inflammatory myopathy, and Marfan syndrome.

Keywords: Connective tissue disorders; Idiopathic inflammatory myopathy; Marfan syndrome; Sjögren syndrome; Systemic lupus erythematosus.

Publication types

Review

MeSH terms

Connective Tissue Diseases*
Female
Humans
Pregnancy
Pregnancy Complications*