Recent Progress in Vascular Tissue-Engineered Blood Vessels

Jun Chen; Grant C Alexander; Pratheek S Bobba; Ho-Wook Jun

doi:10.1007/978-981-13-0445-3_8

Recent Progress in Vascular Tissue-Engineered Blood Vessels

Adv Exp Med Biol. 2018:1064:123-144. doi: 10.1007/978-981-13-0445-3_8.

Authors

Jun Chen¹, Grant C Alexander¹, Pratheek S Bobba¹, Ho-Wook Jun²

Affiliations

¹ Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA.
² Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, USA. hwjun@uab.edu.

PMID: 30471030
DOI: 10.1007/978-981-13-0445-3_8

Abstract

Cardiovascular disease is the number one cause of death in the U.S and results in the loss of approximately one million lives and more than 400 billion U.S. dollars for treatments every year. Recently, tissue engineered blood vessels have been studied and developed as promising replacements for treatment with autologous veins. Here, we summarize the cell sources and methods to make tissue-engineered blood vessels (TEBVs), the recent progress in TEBV related research, and also the recent progress in TEBV related clinical studies.

Keywords: Animal models; Clinical studies; In vitro; Scaffolds; TEBV; Tissue engineered blood vessels; Tissue engineering.

Publication types

Review

MeSH terms

Blood Vessels*
Cardiovascular Diseases / therapy*
Humans
Tissue Engineering*