Posttransplant Malignancy

Surg Clin North Am. 2019 Feb;99(1):49-64. doi: 10.1016/j.suc.2018.09.004.


Posttransplant malignancy is a leading cause of death after solid organ transplantation (SOT). Recipients of SOT are at significantly higher risk of multiple cancers compared with the general population, most notably nonmelanoma skin cancer and posttransplant lymphoproliferative disorders. Risk factors for posttransplant malignancy include history of malignancy, immunosuppression, oncogenic viral infections, sun exposure, and disease-specific associations. Early detection and treatment of malignancies can improve survival.

Keywords: Cancer; Cancer screening; Malignancy; Solid organ transplant; Transplantation.

Publication types

  • Review

MeSH terms

  • Humans
  • Immunosuppression Therapy
  • Neoplasms / etiology*
  • Organ Transplantation / adverse effects*
  • Risk Factors