Eliminating perinatal HIV in the United States: mission possible?

doi:10.1097/QAD.0000000000002080

Review

. 2019 Mar 1;33(3):377-385.

doi: 10.1097/QAD.0000000000002080.

Eliminating perinatal HIV in the United States: mission possible?

Devasena Gnanashanmugam¹, Natella Rakhmanina², Keith W Crawford¹, Steven Nesheim³, Theodore Ruel⁴, Guthrie S Birkhead⁵, Rana Chakraborty⁶, Robert Lawrence⁷, Patrick Jean-Philippe¹, Lakshmi Jayashankar⁸, Ashley Hoover⁹, Anne Statton¹⁰, Patricia DʼSouza¹, Joseph Fitzgibbon¹, Rohan Hazra¹¹, Barbara Warren¹², Somer Smith^{6

13}, Elaine J Abrams¹⁴

Affiliations

¹ Division of AIDS, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland.
² Children's National Medical Center, Elizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia.
³ Centers for Disease Control and Prevention (Division of HIV/AIDS Prevention), Atlanta, Georgia.
⁴ University of California- San Francisco, San Francisco, California.
⁵ School of Public Health, University at Albany, Albany, New York.
⁶ Emory University School of Medicine, Atlanta, Georgia.
⁷ University of Florida, Gainesville, Florida.
⁸ Columbus Technologies Inc., Contractor to National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland.
⁹ Louisiana State Department of Health, Baton Rouge, Louisiana.
¹⁰ Pediatric AIDS Chicago Prevention Initiative, Chicago, Illinois.
¹¹ Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
¹² New York State Department of Health, Albany, New York.
¹³ Theratechnologies, Inc., Montreal, Quebec, Canada.
¹⁴ ICAP at Columbia University, Mailman School of Public Health and Vagelos College of Physicians & Surgeons, Columbia University, New York, New York, USA.

PMID: 30475262
PMCID: PMC6355361
DOI: 10.1097/QAD.0000000000002080

Free PMC article

Review

Eliminating perinatal HIV in the United States: mission possible?

Devasena Gnanashanmugam et al. AIDS. 2019.

Free PMC article

. 2019 Mar 1;33(3):377-385.

doi: 10.1097/QAD.0000000000002080.

Authors

Affiliations

¹ Division of AIDS, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland.
² Children's National Medical Center, Elizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia.
³ Centers for Disease Control and Prevention (Division of HIV/AIDS Prevention), Atlanta, Georgia.
⁴ University of California- San Francisco, San Francisco, California.
⁵ School of Public Health, University at Albany, Albany, New York.
⁶ Emory University School of Medicine, Atlanta, Georgia.
⁷ University of Florida, Gainesville, Florida.
⁸ Columbus Technologies Inc., Contractor to National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland.
⁹ Louisiana State Department of Health, Baton Rouge, Louisiana.
¹⁰ Pediatric AIDS Chicago Prevention Initiative, Chicago, Illinois.
¹¹ Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
¹² New York State Department of Health, Albany, New York.
¹³ Theratechnologies, Inc., Montreal, Quebec, Canada.
¹⁴ ICAP at Columbia University, Mailman School of Public Health and Vagelos College of Physicians & Surgeons, Columbia University, New York, New York, USA.

PMID: 30475262
PMCID: PMC6355361
DOI: 10.1097/QAD.0000000000002080

Abstract

: In 2015, only 53 infants born in the United States acquired HIV - the lowest recorded number of perinatal HIV infections. Recognizing this significant achievement, we must acknowledge that the United States has not yet reached the goal of eliminating perinatal HIV transmission. This analysis describes different approaches to perinatal HIV preventive services among five states and the District of Columbia as case studies. Continuous focus on improving identification, surveillance and prevention of HIV infection in pregnant women and their infants is necessary to reach the goal of eliminating perinatal HIV transmission in the United States.

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Koay WLA, Zhang J, Manepalli KV, Griffith CJ, Castel AD, Scott RK, Ferrer KT, Rakhmanina NY. Koay WLA, et al. J Pediatr. 2021 Jan;228:101-109. doi: 10.1016/j.jpeds.2020.09.041. Epub 2020 Sep 21. J Pediatr. 2021. PMID: 32971142 Free PMC article.
HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE.
Millar JR, Bengu N, Fillis R, Sprenger K, Ntlantsana V, Vieira VA, Khambati N, Archary M, Muenchhoff M, Groll A, Grayson N, Adamson J, Govender K, Dong K, Kiepiela P, Walker BD, Bonsall D, Connor T, Bull MJ, Nxele N, Roider J, Ismail N, Adland E, Puertas MC, Martinez-Picado J, Matthews PC, Ndung'u T, Goulder P; Ucwaningo Lwabantwana Consortium. Millar JR, et al. EClinicalMedicine. 2020 May 8;22:100344. doi: 10.1016/j.eclinm.2020.100344. eCollection 2020 May. EClinicalMedicine. 2020. PMID: 32510047 Free PMC article.

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Eliminating perinatal HIV in the United States: mission possible?

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Eliminating perinatal HIV in the United States: mission possible?

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