Overlooked Issues on Pharmacokinetics Data Interpretation of Protein Drugs-a Case Example of Erythropoietin

AAPS J. 2018 Nov 26;21(1):6. doi: 10.1208/s12248-018-0269-7.
No abstract available

Keywords: erythropoietin; overlooked issues; pharmacokinetic data interpretation; protein drugs.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anemia / drug therapy
  • Animals
  • Area Under Curve
  • Biological Assay / methods*
  • Biological Assay / standards
  • CHO Cells
  • Cricetulus
  • Data Interpretation, Statistical
  • Erythropoiesis / drug effects*
  • Erythropoietin / administration & dosage
  • Erythropoietin / pharmacokinetics*
  • Hematinics / administration & dosage
  • Hematinics / pharmacokinetics*
  • Humans
  • Pharmaceutical Research / methods*
  • Pharmaceutical Research / standards
  • Recombinant Proteins / administration & dosage
  • Recombinant Proteins / pharmacokinetics

Substances

  • EPO protein, human
  • Hematinics
  • Recombinant Proteins
  • Erythropoietin